Professor Alison Ashcroft

Professor Alison Ashcroft has almost 30 years experience of MS development and its application to bio-analytical challenges.

Her research is focused on protein folding and characterising the assembly pathways of macromolecular protein complexes.

Her recent ESI-(IMS)-MS development work on separating and characterising protein conformers and oligomers led to the Journal of the ASMS’s “Ron Hites Award” in 2009 for “outstanding original research”.

Current studies include characterising protein oligomers during amyloid fibril formation, identifying transient intermediates on viral assembly pathways, characterising lactococcal phage baseplate assemblies (≤2 MDa), deciphering bacterial pilus assembly mechanisms, and studying structure/function relationships of membrane proteins.