Dr Lorna Dougan specializes in neutron diffraction and single molecule force spectroscopy to explore the structural and dynamic properties of biological systems.
Dr Dougan’s studies have provided insight into the molecular mechanisms of cryopreservation and the role of solutes in maintaining protein stability and flexibility.
Much of her work is centred on the novel experimental technique of single molecule force-clamp spectroscopy.
Dr Dougan has demonstrated that this technique can be ground-breaking in the insight it can provide in the fields of protein stability, dynamics and flexibility, mechano-chemical reactions and solvent mediation in biological systems.
This work has been extended to probe molecules under the extreme conditions of high and low temperatures, as well as extreme salt and acid solvent conditions.